Magnesium and Vitamin B - Quest 150mg 60 tablets Triple pack offer

	Good for:  Controlling the anxiety, irritability, headaches, sugar-cravings and tension
	Things to be aware of:  Food supplements should not be used as a substitute for a varied diet. p&p from £2.50+VAT no matter how much you buy!

Magnesium and Vitamin B

Magnesium is classed as 'nature's tranquilliser' and so is vital in those aspects of the pre-menstrual symptoms which relate to anxiety, tension, etc.. Women with PMS have been found to have lower levels of red blood cell magnesium than women who don't have symptoms and the supplementation of magnesium has been found to be extremely useful in alleviating many of the PMS symptoms and even more effective when taken with vitamin B6 at the same time.

A magnesium deficiency can cause blood vessels to go into spasms so if you suffer from menstrual migraines magnesium can be useful in preventing these spasms.

A number of studies have shown the effectiveness of vitamin B6 on PMS. Vitamin B6 plays a vital part in synthesising certain brain chemicals (neurotransmitters) that control your mood and behaviour. In order for your body to convert B6 (as pyridoxine) into its active form (pyridoxal-5-phosphate) which your body can use, it needs other nutrients such as magnesium. So if you take B6 on its own but are deficient in other nutrients your body may not be able to use that B6 properly.

Quest Magnesium is amino acid chelated to improve absorption and utilisation, and includes Vitamin B6 to enhance the formulation.

---

Dosage

Directions: One or two tablets daily with food

Suitable for Vegetarians and Vegans

Nutritional Information 
Name                               Amount    R.D.A.
Magnesium                         150 mg     50
Vitamin B6                           16 mg     800

Additional Ingredients:
Microcrystalline Cellulose, Magnesium Sterate, Glazing Agent: Hydroxypropylmethylcellulose. 
 

---

Does it work?

Vitamin B6 is one of the most useful of the B-vitamins for reducing PMS symptoms. It particularly reduces fluid retention, breast swelling and tenderness, bloating and edema in general, as well as anxiety, irritability, insomnia, sugar craving and symptoms caused by refined sugar. Furthermore many,^1,2,3,4,5, but not all,⁶ studies have shown that taking 50 mg/d to 400 mg/d vitamin B6 for several months can relieve symptoms of PMS. Vitamin B6’s mechanism of action may have to do with its ability to increase the conversion of the fatty acid gamma linolenic acid (GLA) to prostaglandin E1—a chemical that may reduce the effects of PMS.⁷

A nutrient with similar activity is magnesium. Several studies have found women with PMS are often deficient in magnesium,^8,9 and supplementing with magnesium may help reduce symptoms.^10,11 Like vitamin B6, magnesium has the ability to increase the conversion of GLA to prostaglandin E1.

1. Barr W. "Pyridoxine supplements in the premenstrual syndrome." Practitioner. 228:425-27, 1984.

2. Gunn AD. "Vitamin B6 and the premenstrual syndrome (PMS)." Int J Vitam Nutr Res. 27:S213-24, 1985.

3. Kleijnen J, Ter Riet G, Knipschild P. "Vitamin B6 in the treatment of the premenstrual syndrome--a review." BJOG. 97:847-52, 1990. www.womenshealth-elsevier.com/doc/journals/bjog1.html

4. Williams MJ, Harris RI, Dean BC. "Controlled trial of pyridoxine in the premenstrual syndrome." J Int Med Res. 13:174-9, 1985.

5. Brush MG, Perry M. "Pyridoxine and the premenstrual syndrome." Lancet. 1:1399, 1985. www.thelancet.com

6. Hagen I, Nesheim B-I, Tuntland T. "No effect of vitamin B-6 against premenstrual tension. A controlled clinical study." Acta Obstet Gynecol Scand. 64:667-70, 1985.

7. Horrobin DF. "Evening primrose oil and premenstrual syndrome." Med J Aust. 153, 10:630-1, 1990. www.mja.com.au

8. Abraham GE, Lubran MM. "Serum and red cell magnesium levels in patients with premenstrual tension." Am J Clin Nutr. 34:2364-6, 1981. www.ajcn.org

9. Sherwood RA et al. "Magnesium and the premenstrual syndrome." Ann Clin Biochem. 23:667-70, 1986.

10. Nicholas A. "Traitement du syndrome pre-menstruel et de la dysmenorrhee par'lion magnesium." First International Symposium on Magnesium Deficit in Human Pathology, 1973.

11. Facchinetti F et al. "Oral magnesium successfully relieves premenstrual mood changes." Obstet Gynecol. 78:177-81, 1991. www.greenjournal.org

---