Colpermin Enteric Coating

An enteric coating is a coating put on a pill or capsule so that it doesn't dissolve until it reaches the small intestine. While the coating may make a pill easier to swallow and will mask bitter-tasting medicine, enteric coatings are primarily used because the drug is likely to cause stomach irritation or because its effectiveness might be reduced by stomach acids or enzymes.

Enteric coatings work because they are selectively insoluble substances, they won't dissolve in the acidic juices of the stomach, but they will when they reach the higher pH of the small intestine.

Most enteric coatings won't dissolve in solutions with a pH lower than 5.5.

Colpermin is coated in eudragit S100, endragit L30 D55 manufactured from copolymers derived from esters of acrylic and methacrylic acid.